Statistics
Kevin M. Sullivan, Emory University
based on code from John C. Pezzullo
Interface
Andrew G. Dean, EpiInformatics.com, and Roger Mir

Pairs of Cases and Controls matched 1:1 on defined characteristics are evaluated for exposure to a risk factor and distributed into the four cells of the table representing the four possible combinations of outcome in a pair. The counts represent PAIRS containing 1 case and 1 control rather than individual cases.

Results include Fisher Exact and midP Exact tests and confidence limits for the odds ratio, and the McNemar test and the Pair-Matched Odds Ratio to evaluate whether an association exists between case status and the presence or absence of the risk factor.